sars cov 2 spike s1 ntd fc  (Sino Biological)

Journal: Translational Neurodegeneration

Article Title: In vivo diagnosis of TDP-43 proteinopathies: in search of biomarkers of clinical use

doi: 10.1186/s40035-024-00419-8

Figure Lengend Snippet: Reported studies on extra-neural TDP-43 pathology immunodetection

Article Snippet: Posa et al . (2018) [ ] , SALS ( n = 7) C9ORF72 -ALS ( n = 1) HC ( n = 6) , Monoclonal immortalized lymphocytes , Proteintech® 10782–2-AP Proteintech® 22309–1-AP , NTD pTDP-43 (S409/410) , Total TDP-43 unchanged in ALS vs HC; Cytoplasmic TDP-43 translocation in ALS vs HC; Increased pTDP-43 + in ALS vs HC.

Techniques: Translocation Assay, Biomarker Discovery, Control, Simple Western, Diagnostic Assay

Journal: Translational Neurodegeneration

Article Title: In vivo diagnosis of TDP-43 proteinopathies: in search of biomarkers of clinical use

doi: 10.1186/s40035-024-00419-8

Figure Lengend Snippet: Reported studies on TDP-43 pathology immunodetection in biofluids

Article Snippet: Codron et al . (2018) [ ] , SALS ( n = 6) HC ( n = 4) , Skin fibroblasts , Proteintech® 10782–2-AP , NTD , No differences between ALS and HC. Results discourage the use of TDP-43 as a biomarker for ALS.

Techniques: Immunodetection, Clinical Proteomics, Enzyme-linked Immunosorbent Assay, Control, Biomarker Discovery, Multiplex Assay, Diagnostic Assay, Western Blot

Journal: Translational Neurodegeneration

Article Title: In vivo diagnosis of TDP-43 proteinopathies: in search of biomarkers of clinical use

doi: 10.1186/s40035-024-00419-8

Figure Lengend Snippet: Reported studies on extra-neural TDP-43 pathology immunodetection

Article Snippet: Codron et al . (2018) [ ] , SALS ( n = 6) HC ( n = 4) , Skin fibroblasts , Proteintech® 10782–2-AP , NTD , No differences between ALS and HC. Results discourage the use of TDP-43 as a biomarker for ALS.

Techniques: Translocation Assay, Biomarker Discovery, Control, Simple Western, Diagnostic Assay

Journal: Translational Neurodegeneration

Article Title: In vivo diagnosis of TDP-43 proteinopathies: in search of biomarkers of clinical use

doi: 10.1186/s40035-024-00419-8

Figure Lengend Snippet: Reported studies on extra-neural TDP-43 pathology immunodetection

Article Snippet: Orrù et al . (2016) [ ] , ALS (not reported) HC (not reported) , Skin fibroblasts , Proteintech® 10782–2-AP Proteintech® 12892–1-AP Proteintech® 22309–1-AP , NTD CTD pTDP-43 (S409/410) , Loss of nuclear TDP-43.

Techniques: Translocation Assay, Biomarker Discovery, Control, Simple Western, Diagnostic Assay

Journal: Translational Neurodegeneration

Article Title: In vivo diagnosis of TDP-43 proteinopathies: in search of biomarkers of clinical use

doi: 10.1186/s40035-024-00419-8

Figure Lengend Snippet: Physiological and pathological species of TDP-43. Upper: Schematic view of physiological structure of TDP-43, including the N-terminal domain (NTD), two RNA recognition motifs (RRM) and the glycine-rich C-terminal domain (CTD). Lower: Pathological species of TDP-43 and the antibodies that are mostly used for the detection of different fragments and aggregates, and the part of the protein they recognize

Article Snippet: Fourier et al. (2019) [ ] , FTD ( n = 9) , Platelets , Proteintech® 10782–2-AP Proteintech® 12892–1-AP , NTD CTD , Pilot study: suitability for detection of TDP-43 in platelets from blood samples of FTD patients by means of Simple Western® approach.

Techniques:

Journal: Translational Neurodegeneration

Article Title: In vivo diagnosis of TDP-43 proteinopathies: in search of biomarkers of clinical use

doi: 10.1186/s40035-024-00419-8

Figure Lengend Snippet: Reported studies on TDP-43 pathology immunodetection in biofluids

Article Snippet: Fourier et al. (2019) [ ] , FTD ( n = 9) , Platelets , Proteintech® 10782–2-AP Proteintech® 12892–1-AP , NTD CTD , Pilot study: suitability for detection of TDP-43 in platelets from blood samples of FTD patients by means of Simple Western® approach.

Techniques: Immunodetection, Clinical Proteomics, Enzyme-linked Immunosorbent Assay, Control, Biomarker Discovery, Multiplex Assay, Diagnostic Assay, Western Blot

Journal: Translational Neurodegeneration

Article Title: In vivo diagnosis of TDP-43 proteinopathies: in search of biomarkers of clinical use

doi: 10.1186/s40035-024-00419-8

Figure Lengend Snippet: Reported studies on extra-neural TDP-43 pathology immunodetection

Article Snippet: Fourier et al. (2019) [ ] , FTD ( n = 9) , Platelets , Proteintech® 10782–2-AP Proteintech® 12892–1-AP , NTD CTD , Pilot study: suitability for detection of TDP-43 in platelets from blood samples of FTD patients by means of Simple Western® approach.

Techniques: Translocation Assay, Biomarker Discovery, Control, Simple Western, Diagnostic Assay